Syneos Health Podcast | Site Realities Series

What does it take to deliver clinical trials where it matters most—at the site?

In today’s environment, success in clinical operations depends on how well we understand, support and partner with investigative sites to keep studies moving forward.

In the Syneos Health Podcast: Site Realities series, we explore the realities shaping trial delivery. From critical site needs to the evolving role of CRAs and study teams, we’ll examine the challenges, priorities and innovations driving stronger site partnerships and better outcomes.

The views expressed in this podcast belong solely to the speakers and do not represent those of their organization.

Episode 1 | Inside the Site Experience: Challenges, Tradeoffs and Opportunities

In this episode, Tammy D’Lugin-Monroe, Head of Trial Enablement Solutions at Syneos Health, sits down with Mimi Fenton, MPH, PhD, CEO of Cedar Health Research, to explore what it truly means to operate on the front lines of clinical research. Drawing on her experience across pharma, CRO and site leadership, Mimi offers a candid view into the operational, financial and human realities that shape today’s clinical trial landscape.

Episode 2 | From Monitor to Strategic Partner: The Evolution of the CRA Role

In this episode, host Tammy D’Lugin-Monroe and Audra Holleman, Head, Country Operations, Americas at Syneos Health explore the evolving role of the clinical research associate (CRA)—and why it matters more than ever. From shifting expectations around site relationships to the growing impact of technology and AI, the conversation highlights how CRAs are moving beyond transactional monitoring to become trusted partners, problem solvers and scientific advisors.

Episode 3 | Building Trust at the Site Level: The CRA as Ambassador and Partner

In this episode, Tammy D’Lugin-Monroe sits down with Przemyslaw Wziatek, Country Head for Poland and Ukraine within Clinical Operations at Syneos Health, to explore how relationships between Clinical Research Associates (CRAs) and Clinical Sites are evolving in today’s increasingly complex research environment.

As competition for high-performing sites intensifies, strong partnerships have become more important than ever. Tammy and Przemyslaw discuss what sites truly expect from CRO partners, why the CRA role has evolved beyond monitoring into that of an ambassador and problem solver, and how trust is built through responsive, thoughtful communication.

Together, they examine the realities sites face every day, from balancing patient care alongside multiple studies to navigating increasing operational complexity and technology demands. The conversation also explores how CROs can better align with site priorities, reduce communication friction and create stronger long-term partnerships that ultimately support study success and improve the patient experience.

Episode 4 | Navigating Complexity: Communication, Escalation Paths and Site Partnership at Scale

Closing out the Site Realities series, Tammy D’Lugin-Monroe continues her conversation with Przemyslaw Wziatek, Country Head for Poland and Ukraine within Clinical Operations at Syneos Health, exploring how sites navigate the complexity of working within large CRO organizations.

 Together, they discuss the importance of clear communication pathways, operational ownership and timely escalation processes in building strong site partnerships. From reducing communication noise to improving site launch meetings and helping sites quickly connect with the right support teams, the conversation highlights practical ways CROs can create a more seamless and supportive site experience.